Cost
How Much Does Ketamine Therapy Cost?
Medically reviewed · Updated 2026
Ketamine clinic pricing is confusing on purpose — few publish real numbers. Here are the actual ranges, written by a physician who serves as a ketamine medical director, so you can budget and spot a clinic that's overcharging.
IV ketamine: the typical numbers
In the US, a single IV ketamine infusion commonly runs $400–$800. The standard induction phase is about six infusions over two to three weeks, which puts the initial series at roughly $2,400–$4,800. Maintenance infusions afterward are individualized and add ongoing cost. IV ketamine for depression is usually out of pocket — it's an off-label use, and insurers rarely cover it.
Esketamine (Spravato): the covered path
Spravato is the FDA-approved nasal-spray form, approved specifically for treatment-resistant depression. Because it's FDA-approved for this use, it is far more likely to be covered by insurance. It's administered in a certified setting with monitoring, which adds facility cost, but insurance coverage often makes your out-of-pocket total substantially lower than paying cash for IV.
How to evaluate a clinic
- Who's supervising? There should be a physician (often an anesthesiologist or psychiatrist) as medical director, with monitoring during infusions.
- What's included? Confirm whether the price covers monitoring, follow-up, and any integration support, or just the drug.
- Is it real medicine or a spa? Legitimate clinics screen you, take a full history, and coordinate with your existing providers.
- Did they mention Spravato? A good clinic will tell you if esketamine could save you money through insurance, even though it earns them less than cash-pay IV.
See it next to the alternatives
Cost only makes sense in context. Treatment Finder puts ketamine's price next to TMS, ECT, and medication strategies so you can weigh what you'd actually pay against what each is likely to do for your situation — and export a summary to discuss coverage with your psychiatrist.
Put this into practice
Treatment Finder maps all 38 options to your situation and exports a PDF for your appointment. $4.99 once, no subscription. Get it on the App Store →
Educational reference, not medical advice. This does not diagnose or treat any condition and is not a substitute for a licensed clinician. In crisis, call or text 988 (US Suicide & Crisis Lifeline).